Medical Treatments for Prostate Cancer

There are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.

Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy.

The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped.

androgen dependent prostate cancer
Clinical and preclinical effects of nordihydroguareacetic acid
The effects of NDGA in vitro and in patients with a androgen dependent prostate cancer ADPC were studied. Methods: In vitro: LAPC-4 cells were incubated

ARS | Publication request: USING DNA MICROARRAY ANALYSES TO
Using dna microarray analyses to elucidate the effects of genistein in androgen-dependent prostate cancer cells: identification of novel targets for cancer

Oncostatic activity of a thiazolidinedione derivative on human
androgen-dependent prostate cancer cell line (LNCaP). It is actu- .. genes in androgen-dependent LNCaP prostate cancer cells. Com-

Glossary of Prostate Cancer Related Terms, A - Prostate Cancer
androgen dependent PC (ADPC): PC cells that depend on androgens for androgen independent prostate cancer (AIPC): PC cells that do not depend on androgen

Androgen Receptor Expression and Cellular Proliferation During
In androgen-dependent tumors, 98.5% of tumor cell nuclei expressed androgen Rapid Androgen Cycling as Treatment for Patients with Prostate Cancer

Saw Palmetto induces growth arrest and apoptosis of androgen
Saw Palmetto induces growth arrest and apoptosis of androgen-dependent prostate cancer LNCaP cells via inactivation of STAT 3 and androgen receptor

Antiandrogen Bicalutamide Promotes Tumor Growth in a Novel
Antiandrogen Bicalutamide Promotes Tumor Growth in a Novel Androgen-Dependent Prostate Cancer Xenograft Model Derived from a Bicalutamide-Treated Patient

P16 Axis in Androgen-Dependent Proliferation of Prostate Cancer Cells
The purpose of this study is to understand the role of the p16 growth control axis in androgen dependent proliferation of prostate cancer cells.

IngentaConnect Androgen-independent prostate cancer DU145 cells
Androgen-independent prostate cancer DU145 cells suppress androgen-dependent growth of prostate stromal cells through production of inhibitory factors for

Cellular Pathway Identified That Makes Prostate Cancer Fatal
in both androgen-dependent and androgen-independent prostate cancer cells. âœOne of the most confounding things about prostate cancer is that after a

Functional dissection of transcriptional profiles in androgen
Functional dissection of transcriptional profiles in androgen-dependent and -independent prostate cancer. Lukas Amler1, David Agus2, Nicholas Dracopoli1,

eMedicine - Prostate Cancer: Metastatic and Advanced Disease
Historically, systemic therapy for metastatic and advanced prostate cancer has involved androgen suppression. In metastatic disease, this palliative therapy

Prostate cancer
80% of prostate cancers are androgen dependent for their growth; Hormonal therapy Lee F, Patel H R. Prostate cancer: management and controversies.

NEJM -- Mechanisms of Androgen-Refractory Prostate Cancer
During androgen-dependent progression, prostate-cancer cells depend primarily on the androgen receptor for growth and survival. When the androgen receptor

Signal transduction pathways in androgen-dependent and
We verified these results in vitro, using the androgen-dependent prostate cancer cell line LNCaP and its androgen-independent clone C4-2 as models of

Prostate Cancer - www.Vitacost.com
One trial distinguished prostate cancer patients with androgen-dependent (an earlier, milder form of the cancer) and androgen-independent (a later,

Our Stolen Future: Bisphenol A may interfere with treatment for
In early stages of prostate cancer, treatment focuses on the androgen sensitivity the same biochemical pathway used by DHT in androgen dependent cells.

Prostate cancer - Wikipedia, the free encyclopedia
For prostate cancer cells whose growth is dependent upon testosterone, and cancerous prostate cells that are androgen independent "suicided" as well.


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