Medical Treatments for Prostate Cancer

There are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.

Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy.

The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped.

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Virgil's Prostate On-Line
A recent study, conducted at M.D. Anderson Cancer Center in Houston, showed significant results in treating patients with androgen independent prostate

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The three trials â” for patients with metastatic androgen-independent prostate cancer â” include separate studies of two monoclonal antibody investigative

Resveratrol sensitizes androgen independent prostate cancer cells
of resveratrol to sensitize androgen independent. prostate cancer (AIPC) cell lines to apoptosis induction. by a range of triggers.

A new weapon against androgen-independent prostate cancer -- Kent
A new weapon against androgen-independent prostate cancer. Heather Kent. Vancouver. A discovery by a scientist at the BC Cancer Agency explains why some

Best treatment for androgen-independent prostate cancer
2007-05-23 15:22:15 - The chemotherapy drug docetaxel currently offers the best treatment for androgen-independent prostate cancer.

Androgen-Independent Prostate Cancer Treated with Resection of the
Androgen-Independent Prostate Cancer Treated with Resection of the Solitary Metastatic Site Raj S. Pruthi, J. Slade Hubbard, Erik Kouba, Eric Wallen

Prostate cancer
80% of prostate cancers are androgen dependent for their growth; Hormonal therapy Lee F, Patel H R. Prostate cancer: management and controversies.

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3 As a result, treatment strategies are needed for men with androgen-independent prostate cancer (AIPC). A minority of men who have progressive disease

Glossary of Prostate Cancer Related Terms, A - Prostate Cancer
androgen independent prostate cancer (AIPC): PC cells that do not depend on androgen for growth. androgen receptor (AR): A structural entity that is the

How Do You Treat Prostate Cancer That Has Progressed On Primary
Progression of disease on ADT indicates that androgen-independent prostate cancer (AIPC) cells escaped apoptosis by some mechanism.

Androgen-independent prostate cancer is a heterogeneous group of
Understanding the biology of prostate cancer metastasis has been limited by the lack of tissue for study. We studied the clinical data, distribution of

eMedicine - Prostate Cancer: Metastatic and Advanced Disease
Although it can slightly improve the likelihood of survival, most men progress to hormone-refractory prostate cancer, also termed as androgen-independent

Signal transduction pathways in androgen-dependent and
We verified these results in vitro, using the androgen-dependent prostate cancer cell line LNCaP and its androgen-independent clone C4-2 as models of

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An algorithm was designed for a randomized selection trial to identify promising treatments for androgen-independent prostate cancer for more advanced

Timing Of Taxane Administration In Androgen-Independent Prostate
UroToday.com - Dr. Mitchell Benson, Columbia University moderated a session on Timing of Taxane Administration in Androgen-Independent Prostate Cancer: When

Adaptive Therapy For Androgen Independent Prostate Cancer: A
UroToday.com- In the November 2007 issue of the Journal of the National Cancer Institute, Dr. Thall and colleagues report on changing chemotherapy regimens

NEJM -- Mechanisms of Androgen-Refractory Prostate Cancer
However, these tumors eventually become androgen-independent and grow despite androgen ablation. When prostate cancer is localized in the prostate,

U-M CCC - Prostate Cancer Home Page
One of the central questions in the study of androgen-independent prostate cancer concerns the point at which androgen-independent cells arise.


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