Medical Treatments for Prostate CancerThere are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy. The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped. |
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Dutasteride Induces Apoptosis In Androgen Sensitive Prostate Seven Keys to Treating Prostate Cancer. Johns Hopkins .pdf induces apoptosis in androgen sensitive, but not androgen insensitive prostate cancer (CaP) Androgen-insensitive prostate cancer cells transiently respond to Androgen-insensitive prostate cancer cells transiently respond to castration treatment when growing in an androgen-dependent prostate environment. ScienceDirect - Cancer Letters : Differential effects of blueberry Differential effects of blueberry proanthocyanidins on androgen sensitive and insensitive human prostate cancer cell lines. Barbara M. Schmidta, The G{gamma}/T-15 Transgenic Mouse Model of Androgen-independent T-15 transgenic mice are a useful model for testing vitamin D-based therapies in androgen-insensitive prostate cancer but are not suitable for studies of The Journal of Urology : MITOGENIC SIGNALING IN ANDROGEN SENSITIVE Androgen sensitive (LNCaP) and insensitive (PC-3) prostate cancer cell lines were used in these studies. Epidermal growth factor (EGF), lysophosphatidic Biomedical Seminar Calendar - Stanford University Medical Center Androgen Signaling in Androgen-insensitive Prostate Cancer. Date:. Thu., 27-Jan-2005. Time:. 5:30 PM-6:30 PM. Location:. Cancer Center CC2103. Department: A promoting role of androgen receptor in androgen-sensitive and Taken together, our results elucidate an important role for the AR in androgen-insensitive prostate cancer cells, and suggest that AR can be used as a Suppression of caveolin expression induces androgen sensitivity in Our results identify a new candidate gene for hormone-resistant prostate cancer in man and indicate that androgen insensitivity can be an inherent property New Directions in the Management of Advanced Prostate Cancer The future for androgen-insensitive prostate cancer was bleak, at best. Disease recurrence while on androgen deprivation was a death sentence. FuturePundit: Androgen Insensitive Prostate Cancer Stopped With So one obvious implication of this research is that resveratrol might restore the androgen sensitivity of androgen insensitive prostate cancer by turning on Androgen-sensitive Prostate Cancer Survival And Progression Is Dr. Christopher Evans, University of California, Davis School of Medicine presented data showing that androgen insensitive prostate cancer cells can secrete Dutasteride Induces Apoptosis In Androgen Sensitive Prostate Dutasteride Induces Apoptosis In Androgen Sensitive Prostate Cancer Cell Lines in androgen sensitive, but not androgen insensitive prostate cancer (CaP) How Do You Treat Prostate Cancer That Has Progressed On Primary For example, in laboratory experiments, expression of an activated Hras oncogene in androgen-sensitive LNCaP prostate cancer cells allows these cells to Androgen Receptor Mutations Identified in Prostate Cancer and The AR N-terminal mutations identified in androgen insensitivity (AIS) (top) and prostate cancer (PCa) (bottom) are shown. A list of AR point mutations can Androgen-induced inhibition of cell proliferation in an androgen Androgen-induced inhibition of cell proliferation in an androgen-insensitive prostate cancer cell line (PC-3) transfected with a human androgen receptor ERR{gamma} Suppresses Cell Proliferation and Tumor Growth of Suppresses Cell Proliferation and Tumor Growth of Androgen-Sensitive and Androgen-Insensitive Prostate Cancer Cells and Its Implication as a Therapeutic Raf-1 expression may influence progression to androgen insensitive development of androgen insensitive prostate cancer (AIPC). We have previously reported .. insensitive prostate cancer; AR, androgen-receptor; phospho Lysophosphatidic acid promotes survival of androgen-insensitive androgen-insensitive prostate cancer cells. Cell survival was measured by FACS effective for the treatment of androgen-insensitive prostate cancer. Effect of the Chinese Herbal Extract on androgen-insensitive We therefore investigated the effect of the seven Chinese herbal extract in PC- SPES on androgen insensitive prostate cancer (AIPC) cell lines and in nude |
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