Medical Treatments for Prostate CancerThere are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy. The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped. |
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Androgens and Prostate Cancer It remains to be demonstrated whether androgen independent prostate cancer is the direct consequence of molecular events mediated by, or independent of, Insulin-like growth factor-1 messenger RNA isoforms in rat Although the growth and differentiation of the normal prostate is. strictly dependent on androgen, prostate tumors are characterized by Identification of androgen-regulated genes in the prostate cancer A common therapy for nonorgan-confined prostate cancer involves androgen androgen responsive prostate cancer line LNCaP, at both RNA and protein levels. Steroids : The androgen receptor: a potential target for therapy The androgen receptor plays a pivotal role in the prostate. . Inhibition of the AR in androgen-refractory prostate cancer cells has been shown to shut JSTOR: T Cell Infiltration of the Prostate Induced by Androgen Burrows and Kennaway (20) and ?1; www.pnas.org/cgi/doi/10.1073/pnas.251 140998 :ate induced by androgen prostate cancer nela S. Kwont, Eugene S. Y. Park*t, Androgen Induces Adaptation to Oxidative Stress in Prostate Cancer Testosterone-repressed prostate message-2 is an anti-apoptotic gene involved in progression to androgen independence in prostate cancer. Cancer Res. USRF - Androgen Deprivation Treatment. Part I. History Awareness of the androgen-dependence of prostate tissue can be traced back to the work of John Hunter, the Scot known as the father of scientific surgery, Anti-androgens in the treatment of prostate cancer The negative effects of androgen withdrawal on prostate. gland growth have been known since the days . withdrawal of androgens Prostate 1983; 4: 579â“94 Serum Androgens: Associations With Prostate Cancer Risk and Hair Androgens, Prostate Cancer Risk and Baldness. 499. Table 3. Hormonal . of serum androgen. lev-. els in men. with. and. without. prostate. cancer. Serum androgens and prostate cancer -- Nomura et al. 5 (8): 621 Serum androgens and prostate cancer. AM Nomura, GN Stemmermann, PH Chyou, BE Henderson and FZ Stanczyk Japan-Hawaii Cancer Study, Kuakini Medical Center, Nature Clinical Practice Urology | Can androgen receptor levels in Recent studies confirmed that AR expression levels are consistently elevated in association with the development of androgen resistance in prostate cancer Androgen-regulated gene expressed in prostate tissue - Patent 6566130 This invention relates to androgen-regulated nucleic acids, a polynucleotide array containing these androgen-regulated nucleic acids, and methods of using Casodex, cosudex, (bicalutamide) - anti androgen, prostate cancer Casodex, Cosudex (bicalutamide) information, an anti androgen for prostate cancer provided by AstraZeneca. Inhouse Pharmacy Androcur - Cyproterone Acetate - Anti-Androgen Cyproterone acetate inhibits competitively the effect of androgens at androgen-dependent target organs, e.g. it shields the prostate from the effect of ACS :: Hormone (Androgen Deprivation) Therapy The main androgens are testosterone and dihydrotestosterone (DHT). Androgens, produced mainly in the testicles, stimulate prostate cancer cells to grow. Our Stolen Future: Bisphenol A may interfere with treatment for In early stages of prostate cancer, treatment focuses on the androgen sensitivity of prostate cancer cells. These cells require serum androgen to New androgen prostate cancer pathway found PhysOrg news: New androgen prostate cancer pathway found. New androgen prostate cancer pathway found - UPI.com The pathway is used by the sex hormone androgen, which increases levels of harmful chemicals called reactive oxygen species in the prostate gland that play Androgen Receptor Outwits Prostate Cancer Drugs Most patients with metastatic prostate cancer receive drugs that block production of androgen, which promotes cancer cell proliferation. |
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