Medical Treatments for Prostate CancerThere are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy. The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped. |
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IngentaConnect Prognostic Significance of Bone Metastasis Patterns Patients and methods : Ninety-four prostate cancer patients with bone metastasis included in this study were sub-classified into two groups according to the Collaborative Prostate Cancer Project Earns $7.6 Million Federal Grant Titled "Prostate Cancer Bone Metastasis: Biology and Targeting," the collaboration Heparan Sulfate Proteoglycans in Prostate Cancer Bone Metastasis, Hepatocyte Growth Factor and Interleukin-6 in Prostate Cancer Bone Title : Hepatocyte Growth Factor and Interleukin-6 in Prostate Cancer Bone Metastasis. Descriptive Note : Annual rept. 15 Feb 2003-14 Feb 2004 Hepatocyte Growth Factor and Interleukin-6 in Prostate Cancer Bone The support provided by the grant fostered the PI's career development to an independent investigator in the field of prostate cancer metastasis to bone. Osteoprotegerin in Prostate Cancer Bone Metastasis -- Corey et al Osteoprotegerin in Prostate Cancer Bone Metastasis. Eva Corey1, Lisha G. Brown1, Jeffrey A. Kiefer1,2, Janna E. Quinn1, Tiffany E.M. Pitts1, Julie M. Blair1 Osteoprotegerin in Prostate Cancer Bone Metastasis -- Corey et al Cancer Res. Home page R. L. Vessella and E. Corey Targeting factors involved in bone remodeling as treatment strategies in prostate cancer bone metastasis. Osteoblasts in Prostate Cancer Metastasis to Bone Metastasis to bone is common in lung, kidney, breast and prostate cancers. However, prostate cancer is unique in that bone is often the only clinically ACS :: How Is Bone Metastasis Treated? Osteoblastic metastases occur most frequently in prostate cancer that has spread to The most common way to deliver radiation to a bone metastasis is to ACS :: What Is Bone Metastasis? For example, if prostate cancer spreads to the bones, it is still called prostate cancer, Primary bone cancer is much less common than bone metastasis. Bonetumor.org - The Web's Most Comprehensive Bone Tumor Resource Patients with metastatic bone tumors do not need to lose hope, tumor survival, accounting for the high rate of prostate cancer metastasis to the spine. eMedicine - Prostate Cancer: Metastatic and Advanced Disease Bone scan: At initial presentation with prostate cancer, the value of a bone metastatic prostate cancer and microscopic lymph node metastasis from 20% Hormone-Refractory Prostate Cancer with Bone Metastases - Prostate PAIN FROM BONE METASTASIS IS ONE OF THE MOST DIFFICULT CLINICAL PROBLEMS IN PATIENTS . Gandhok N and Sartor O.Bone-targeted therapy for prostate cancer. b. Treating Bone Metastases - Prostate Cancer Foundation Men who experience pain from a bone metastasis will often be treated with radiation targeted directly to the metastasis. This will kill the prostate cancer National Prostate Cancer Coalition: Advanced Prostate Cancer: Bone To learn about research into new ways to treat bone metastasis, please visit the following pages in our new Research Section:. Prostate Cancer Research: Advanced Prostate Cancer: Understanding Prostate Cancer Metastasis Advanced prostate cancer with bone metastasis or lymph node metastasis is more Advanced prostate cancer bone metastasis and lymph node metastasis, Clinical Oncology : Diagnosis of Bone Metastasis in Men with Diagnosis of Bone Metastasis in Men with Prostate Cancer by Measurement of Serum ICTP in Combination with Alkali Phosphatase and Prostate-specific Antigen Targeting Bone Metastasis in Prostate Cancer with Endothelin Recent advances in the understanding of prostate cancer biology and its progression to bone metastasis have led to the development of drugs directed against Pathogenesis and treatment of prostate cancer bone metastases The propensity of prostate cancer cells to metastasize to bone is leading to the design of novel therapies targeting both the cancer cell as well as the Prostate Cancer Chemotherapy: Advanced Prostate Cancer and Bone Sometimes the disease will metastasize to the bones and is called advanced prostate cancer with bone metastasis. Bone metastasis can occur during hormone |
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