Medical Treatments for Prostate Cancer

There are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.

Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy.

The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped.

cancer cell prostate
Green Tea Plus Painkiller Slows Prostate Cancer Cell Growth
A component of green tea combined with a low dose of a COX-2 inhibitor act in concert to slow the spread of prostate cancer cells in animal models.

Myc-driven murine prostate cancer shares molecular features with
Cancer Cell. 2005 Dec;8(6):485. Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Ellwood-Yen K, Graeber TG,

Tocopherol-associated protein suppresses prostate cancer cell
Interestingly, without vitamin E treatment, overexpression of TAP in prostate cancer cells significantly suppressed cell growth; knockdown of endogenous TAP

Wwox Suppresses Prostate Cancer Cell Growth through Modulation of
In this study, pathways through which Wwox contributes to control of prostate cancer cell growth have been investigated. We found that Wwox interacts with

Cancer Cell International | Full text | Prostate cancer cells show
Finally, we demonstrate that uPAR is up-regulated by a significant subpopulation prostate cancer cells following matrix detachment and maintenance in

Cancer Cell : Prostate-specific deletion of the murine Pten tumor
B: Immunohistochemical analyses indicate that Pten null prostate cancer cells are proliferative, as indicated by Ki67-positive immunostaining (right panels)

Laboratory Investigation - Abstract of article: CXCL12-CXCR4
The current study evaluates the molecular mechanisms of CXCL12 and CXCR4 in prostate cancer cell migration and invasion. We report that functional CXCR4 is

Oncogene - Abstract of article: Androgen receptor mutation (T877A
Androgen receptor mutation (T877A) promotes prostate cancer cell growth and cell prostate cancer, androgen receptor, mutation, p53, cell proliferation,

Diet, Exercise Slow Prostate Cancer As Much As 30%
At the end of the 11-day regimen, prostate cancer cells immersed in serum Prostate cancer cells exposed to serum from the long-term group showed a 40

BioMed Central | Full text | Analysis of the prostate cancer cell
We present the utility of massively parallel sequencing by synthesis for profiling the transcriptome of a human prostate cancer cell-line, LNCaP,

About PCF - Prostate Cancer Foundation
Development of analytical methods that identify the proteins in blood or the prostate that correlate to treatment effect or behavior of the cancer cell,

|| DukeMedNews || Experimental RNA-Based Drug Kills Prostate
DURHAM, N.C. -- Acting as a genetic Trojan horse, an experimental RNA-based drug -- the first of its kind -- tricks its way into prostate cancer cells and

Loss of BRCA2 promotes prostate cancer cell invasion through up
BRCA2 expression inhibits prostate cancer cell migration. (a) Wild-type PC-3 cells were transiently transfected for 48 or 96 h with non-

Unique Grape Skin Extract Inhibits Prostate Cancer Cell Growth in
Laboratory experiments show that an extract of the skin of muscadine grapes can inhibit growth of prostate cancer cells in the laboratory.

Cancer Cell -- Acevedo et al.
Fibroblast Growth Factor Receptor-1 (FGFR1) is commonly overexpressed in advanced prostate cancer (PCa). To investigate causality, we utilized an inducible

Cancer Cell -- Varambally et al.
All rights reserved. Cancer Cell, Vol 8, 393-406, November 2005. Article. Integrative genomic and proteomic analysis of prostate cancer reveals signatures

Pepper component hot enough to trigger suicide in prostate cancer
Capsaicin induced approximately 80 percent of prostate cancer cells Prostate cancer cells that are androgen independent reacted to capsaicin in a

Cancer - Wikipedia, the free encyclopedia
Sipuleucel-T is a vaccine-like strategy in late clinical trials for prostate cancer in which dendritic cells from the patient are loaded with prostatic acid

Prostate cancer - Wikipedia, the free encyclopedia
8 In prostate cancer the cells of these prostate glands mutate into cancer . For prostate cancer cells whose growth is dependent upon testosterone,


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