Medical Treatments for Prostate Cancer

There are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.

Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy.

The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped.

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The Cancer Council New South Wales :: Understanding Prostate
Understanding Prostate Cancer - Information Checklist. Is my cancer hereditary? If, so what do you recommend? á© The Cancer Council NSW.

Genetics of Prostate Cancer - National Cancer Institute
Psychosocial issues associated with genetic testing and counseling of individuals who may have hereditary prostate cancer syndrome are also discussed.

The Clinical Genetics of Prostate Cancer (hereditary, familial
Although research on hereditary prostate cancer has improved our knowledge of the genetic aetiology of the disease, a lot of questions still remain

RNASEL mutations in hereditary prostate cancer -- Chen et al. 40
Additional functional data in support of the hypothesis that RNASEL mutations contribute to hereditary prostate cancer include: (1) evidence of loss of

eMedicine - Prostate Cancer: Biology, Diagnosis, Pathology
Alteration of genes on chromosome 1, 17, and the X chromosome have been found in some patients with a family history of prostate cancer. The hereditary

Screening for prostate cancer in Dutch hereditary prostate cancer
men in hereditary prostate cancer (HPC) families. The benefits .. Screening Act. Population screening act: hereditary prostate cancer. (Report no.

Hereditary and Familial Prostate Cancer: Biologic Aggressiveness
The terms ÁœfamilialÁ« and ÁœhereditaryÁ« prostate cancer both imply increased risk but are not synonymous. Familial prostate cancer refers to a clustering of

The Genetics of Prostate Cancer - PLWC
Most prostate cancer (about 75%) is considered sporadic, meaning that the damage to the genes occurs by chance after a person is born. Hereditary prostate

Molecular biology of Prostate Cancer - Cancer GeneWeb - Guide to
Hereditary prostate cancer accounts for about 9% of cases. Other specific gene(s) associated with hereditary prostate cancer have yet to be identified.

genome.gov | Hereditary Prosate CA Study FAQ
National Cooperative Study of Hereditary Prostate Cancer in African-Americans What can I do if I am at risk of getting hereditary prostate cancer?

Hereditary prostate cancer: a new piece of the puzzle - Nature
The hereditary form of prostate cancer is remarkably heterogeneous. This adds to the other obstacles of linkage detection, which include a high rate of

HPC1 - Hereditary prostate cancer 1 - aka: PCS1 - Cancer GeneticsWeb
Overview: A possible susceptibility locus for hereditary prostate cancer; HPC1 on chromosome 1q24-q25 was first proposed in 1996.

genome.gov | Hereditary Prostate Cancer in African-Americans Study
Overview of the National Cooperative Study of Hereditary Prostate Cancer in African-Americans, which is sponsored by Howard University and the National

Urology at Hopkins: Brady Urological Institute
HEREDITARY PROSTATE CANCER STUDY. The Johns Hopkins Department of Urology is actively recruiting families with familial prostate cancer and benign prostate

ACS :: Do We Know What Causes Prostate Cancer?
But there are many other gene mutations that may account for some cases of hereditary prostate cancer. None of these is a major cause, and more research on

Hereditary Prostate Cancer
Studies have shown that some cases of prostate cancer may be hereditary. Topics include risk factors and genetic testing.

Sloan-Kettering - Prostate Cancer & Heredity
It estimated that between 5 to 10 percent of all prostate cancer cases are considered hereditary. This means that in some families, a genetic predisposition

Hereditary prostate cancer definition - Cancer Information
Hereditary prostate cancer: A genetic form of prostate cancer. The risk of prostate cancer is clearly genetic. Men with a father or brother with prostate

ACS :: Family History Of Prostate Cancer Increases Chance Of Early
Prostate cancer's hereditary aspect has only been studied since 1992. Researchers are still trying to piece together exactly how men are affected by this


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