Medical Treatments for Prostate Cancer

There are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.

Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy.

The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped.

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Androgen-Induced Regrowth in the Castrated Rat Ventral Prostate
To assess the relative uptake of T and DHT by the prostate, a comparison was made of intraprostatic DHT levels resulting from T and DHT implants.

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Both conditions have been successfully treated medically with a drug that lowers the level of DHT available to prostate tissue and hair follicles.

Proscar Finasteride belongs to a group of medicines known as the 5
In the absence of DHT the prostate shrinks. Therefore, by decreasing the amount of DHT, finasteride helps shrink the prostate. The prostate gland is found

Link between Prostate Health and Hair Loss
Hair Loss Linked to DHT. Most men may not realize that both enlarged prostate, technically known as benign prostatic hyperplasia (or BPH for short),

Composition for inhibiting production of dihydrotestosterone to
The composition is used to prevent excessive levels of DHT in prostate tissue, a major contributing cause of benign prostate hyperplasia (BPH).

Selective reduction of AKR1C2 in prostate cancer and its role in
AKR1C2 expression in prostate cancer and its potential role in modulating local availability of. DHT. Prostate 54: 275â“289, 2003. # 2003 Wiley-Liss, Inc.

CLINICAL REVIEW: 67 Approach to Chemoprevention of Prostate Cancer
men, because DHT is the major prostate mitogen. However,. recent studies by Rittmaster et aI with prostate DHT in these patients. The absolute levels of

Blackwell Synergy - Andrologia, Volume 39 Issue 5 Page 181-184
In conclusion, treatment with testosterone undecanoate generates physiological levels of DHT. Prostate safety parameters did not undergo changes.

Mathematical model for the androgenic regulation of the prostate
Concentration of dimerized complex DHT:AR-T:AR in prostate, CDT, 2.69, Steady state Concentration of dimer DHT:AR-DHT:AR bound to cd DNA in prostate

IsoProst -- BPH, Prostate Cancer, DHT
The hormone prolactin has been shown to increase the uptake of testosterone to DHT in the prostate. Zinc has been shown to inhibit prolactin secretion by

Effects of castration compared with total androgen blockade on
imens to lower prostate DHT concentration. Patients with. BPH were treated for one week prior their effect on prostate DHT concentration, since reducing

Low DHT levels linked to reduced prostate cancer survival
Low serum levels of dihydrotestosterone are associated with decreased survival in prostate cancer patients, although the prognostic value of such levels at

DHT in prostate cancer tissue- a guide to management and therapy
In 24 untreated stage Dz prostate cancer patients with prostate DHT DHT concentrations were also measured in prostate tissue of patients with advanced

No link between short-term testosterone use and prostate cancer
The groups were comparable at baseline for age, serum T and DHT, Prostate-Specific Antigen (PSA), Prostate Volume (PV) and median prostate levels of T and

DHT-3-Effect of Dihydrotestosterone (DHT) on Prostate Tissue
We hypothesize that increases in serum DHT will not increase intraprostatic DHT or prostate epithelial proliferation, and will be associated with decreases

What Causes The Prostate To Enlarge?
Changes in the role of DHT. Prostate gland development requires the conversion of testosterone into DHT (dihydrotestosterone), in the presence of a specific

DHT - PROSTATE - SAW PALMETTO - Thread
Further, it has been suggested that too much DHT could cause prostate cells to divide at an abnormal rate leading to enlargement of the prostate gland.

NATURAL PROSTATE HEALTH
A traditional Native American remedy, saw palmetto reduces prostate enlargement by inhibiting the synthesis of growth-stimulating DHT and promoting DHT

DHT in prostate cancer tissue--a guide to management and therapy.
In 24 untreated stage D2 prostate cancer patients with prostate DHT levels greater than 2.5 ng/g, 20 initially responded to therapy with partial objective


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