Medical Treatments for Prostate Cancer

There are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.

Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy.

The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped.

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News
NEW YORK NOV 27, 2007 (Reuters Health) - More than one third of patients with early prostate cancer receive treatment that may not be appropriate based on

Treatment for early prostate cancer : Cancerbackup
General information on treatment for early (localised) prostate cancer.

Older Men With Early Prostate Cancer Survived Longer With
A new study shows older men with early stage prostate cancer survive longer if they are treated versus not being treated in favor of the "watchful waiting"

Early prostate cancer antigen (EPCA): A better prostate cancer
The new EPCA prostate cancer test may be more accurate than PSA test.

NEJM -- Radical Prostatectomy versus Watchful Waiting in Early
Background In 2002, we reported the initial results of a trial comparing radical prostatectomy with watchful waiting in the management of early prostate

Treatment `mismatch' in early prostate cancer
atients with early prostate cancer face an unusually broad range. of treatment choices for which In a prospective cohort study of early prostate cancer

ACS :: Can Prostate Cancer Be Found Early?
The USPSTF has concluded that studies completed so far do not provide enough evidence to know whether the benefits of testing for early prostate cancer

Early Prostate Cancer Diagnosis Ontario
EPCDO advocates for covering PSA screening tests under OHIP and increased awareness of the value of early diagnosis of prostate cancer.

CLINICAL GUIDELINE: PART 1: Early Detection of Prostate Cancer
Assessment of the value of early prostate cancer detection, through derivation of test likelihood ratios and a cost-effectiveness analysis,

UpToDate Patient information: Early prostate cancer treatment
There are three standard approaches to treating early prostate cancer: surgical removal of the prostate gland, radiation therapy with or without hormone

Early Prostate Cancer: Questions and Answers - National Cancer
A fact sheet that describes risk factors for prostate cancer, and symptoms and treatment options for localized disease. Discusses available screening tests.


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