Medical Treatments for Prostate Cancer

There are many different medical treatments for prostate cancer that involve the clinical care of a healthcare professional. These treatments include expectant therapy, surgery, radiation therapy, hormone therapy, and chemotherapy. Expectant therapy is to carefully observe and monitor the prostate cancer. Because prostate cancer cells often spread very slowly, many older men who have the disease may not need more extensive treatment. However, expectant therapy usually includes routine physician examinations, including digital rectal exams and PSA tests. The different types of surgery for prostate cancer are radical prostatectomy - an open-surgery procedure in which the entire prostate gland and surrounding tissue are removed. Transurethral resection of the prostate (TURP) - surgery to remove part of the prostate gland that surrounds the urethra. Cryosurgery - this procedure involves killing the cancer cells by freezing them with a small metal tool placed in the tumor. Side effects of prostate cancer surgery include incontinence and impotence. Incontinence is the inability to control urine and may result in dribbling of urine, especially immediately after surgery. Normal control usually returns within weeks or months after surgery. Impotence is the inability to achieve an erection. For a month, or so, after surgery, most men are not able to get an erection. Eventually, approximately 40 to 60 percent of men will be able to get an erection sufficient for sexual intercourse, but without ejaculation of semen, since removal of the prostate gland prevents that process.

Radiation therapy uses high energy rays to kill or shrink cancer cells, and to decrease their ability to divide. Radiation is often used to treat prostate cancer that is still confined to the prostate gland, or has spread only to nearby tissue. If the disease is advanced, radiation may be used to reduce the size of the tumor and to provide relief from symptoms. Possible side effects of radiation for prostate cancer may include diarrhea, with or without blood in the stool, and colitis, problems associated with urination, a degree of impotence (inability to get an erection), which may occur within two years of radiation therapy.

The goal of hormone therapy is to lower the level of male hormones in the body, particularly testosterone. Hormone therapy does not cure the cancer, and is often used to treat persons whose cancer has spread or recurred after treatment. Produced mainly in the testicles, testosterone causes prostate cancer cells to grow. Thus, reduced testosterone levels can make the prostate cancer shrink and become less active. Most studies show that hormone therapy works better if it is started early. Chemotherapy is the use of powerful, anti-cancer medications to kill cancer cells.. Hospitalization may be needed to monitor treatment and chemotherapy's side effects. Common side effects of chemotherapy include: nausea and vomiting, hair loss, anemia, reduced ability of blood to clot, mouth sores, increased likelihood of developing infections, fatigue. Most side effects disappear once treatment is stopped.

gleason 7 prostate cancer
The Journal of Urology : Gleason Score 7 Prostate Cancer on Needle
Gleason Score 7 Prostate Cancer on Needle Biopsy: Is the Prognostic Difference in Gleason Scores 4 3 and 3 4 Independent of the Number of Involved Cores?

International Journal of Radiation Oncology*Biology*Physics : A
A Comparison of Biochemical Relapse Free Survival (bRFS) Between Primary Gleason 3 and Primary Gleason 4 for Biopsy Gleason 7 Prostate Cancer

eMJA: Revisiting the role of radical surgery in early stage
The study also found that prostate cancer graded as Gleason sum 7 and above (moderately to poorly differentiated) is lethal.

CAT.INIST
Patients with Gleason score 7 prostate cancer should be considered a specific prognostic category. We believe that this distinction is critical to obtain

prostate cancer with a gleason score of 7 - Prostate Cancer - MedHelp
This is a discussion on MedHelp about prostate cancer with a gleason score of 7. Community members of MedHelp provide help, support, guidance and discussion

Gleason Scoring System Predicts a Worse Outcome in Prostate Cancer
"The main finding of the paper is that if biopsy shows Gleason 7 prostate cancer, which is moderate disease, and also tertiary grade 5, which is a marker of

Shift In Prostate Cancer Gleason Grades From 1989 To 2001
Shift In Prostate Cancer Gleason Grades From 1989 To 2001 For Gleason score 7 the 5-year BRFS improved form 51% to 66% over the two time periods.

Biopsy, Gleason and Your Prostate
Biopsy and related tests to find out if you have prostate cancer and what A Gleason score (or sum) of 3 + 4 = 7 is a different grade of cancer than 4 +

PSA density aids detection of Gleason 7 prostate cancer in
Using the same PSAD cut-off, the AUC for the detection of Gleason 7 prostate cancer was 0.769. Conclusions: A clear and intuitive association between PSAD

IngentaConnect Should Gleason score 7 prostate cancer be
Should Gleason score 7 prostate cancer be considered a unique grade category? - the John Hopkins experience after 10 years

IngentaConnect Gleason score 7 prostate cancer: a heterogeneous
Gleason score 7, in different proportions of grades 3 and 4, is the score most frequently assigned to prostate cancer in our radical prostatectomy specimens

Gleason Grading of Prostate Cancer Illustrated Phoenix5
The most widely used grading method for prostate cancer is known as the Gleason grading system (see Gleason Scores, page 7).

Gleason Grading
Primary Gleason pattern as a predictor of disease progression in Gleason score 7 prostate cancer: a multivariate analysis of 823 men treated with radical

Prostate Cancer Treatment (PDQ^)
Men with Gleason scores of 8 to 10, however, had a prostate cancer-specific mortality of 121 per 1000 person years, and men with Gleason scores of 5 to 7

Prostate cancer guide - MayoClinic.com
Gleason score at diagnosis, Cancer characteristics, Deaths from prostate cancer. 2 to 4, Tends to be slow growing, 6 deaths per 1000 men. 5 to 7, Moderately

Prostate Cancer: Gleason grade
When the pathologist looks at the biopsy he grades the cancer by comparing The vast majority of prostate cancers are Gleason grade 6 -7, or moderate.

Virgil's Prostate On-Line
Gleason 7: A New Risk Category? A man is told he has prostate cancer. Besides the basic PSA blood test, the DRE (digital rectal exam) and a biopsy,

Treatment Options for Prostate Cancer: Evaluating the Evidence
Patient information: A handout on prostate cancer, written by the authors of this .. In contrast, patients with Gleason 7 to 10 cancer should consider

Gleason Grading, Understanding it, from the Prostate Cancer
Understanding Gleason Grading, from Prostate Cancer Infolink web site, might be 7 (4 + 3), where the primary pattern has a Gleason grade of 4 and the


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